Hypopharyngeal Synechiae in Lyell Syndrome (Toxic Epidermal Necrolysis).

نویسندگان

  • Zacharias Vourexakis
  • Frédéric Heymans
چکیده

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Toxic Epidermal Necrolysis and Stevens-Johnson Syndrome

The term toxic epidermal necrolysis (TEN) was introduced in 1956 by Lyell to describe four patients with a syndrome featured by extensive epidermal detachment with mucous membrane involvement, leaving the skin surface looking scalded. Necrolysis denotes necrosis and full thickness detachment of the epidermis. Toxic means severe constitutional symptoms and complications. Stevens-Johnson syndrome...

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Long Term Hypopharyngeal Dysfunction in a Pediatric Patient after Toxic Epidermal Necrolysis: A Case Report and Literature Review

We report the case of an 8-year-old male who experienced failure to thrive and dysphagia following idiopathic Toxic Epidermal Necrolysis (TEN). Despite a normal barium esophagram preoperatively, a significant degree of hypopharyngeal scarring was noted during direct laryngoscopy and bronchoscopy one year after initial presentation. Hypopharyngeal dysfunction following TEN has been reported in a...

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Survey on Etiology of Stevens-Johnson syndrome and Toxic Epidermal Necrolysis in Pediatric Patients: A Six-Year Study from Iran

Background Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are among the most severe dermatologic reactions to the drugs. Data about SJS and TEN among pediatric population especially in Iran is limited. This study aimed to investigate the clinical and para-clinical characteristics of pediatric patients with SJS/TEN. Materials and Methods From 2010 to 2016, all SJS and TEN c...

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Toxic epidermal necrolysis: a paradigm of critical illness

Toxic epidermal necrolysis is an adverse immunological skin reaction secondary in most cases to the administration of a drug. Toxic epidermal necrolysis, Stevens-Johnson syndrome, and multiform exudative erythema are part of the same disease spectrum. The mortality rate from toxic epidermal necrolysis is approximately 30%. The pathophysiology of toxic epidermal necrolysis is similar in many res...

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Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe adverse cutaneous reactions to drugs. We describe the case of a 19 year old patient with SJS/TEN overlap syndrome, who developed severe interstitial pneumonia after she had received antiepileptic drugs. A cytomegalovirus infection was diagnosed by Real Time Polymerase Chain Reaction (RT-PCR) detection on Bronchoalveo...

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عنوان ژورنال:
  • Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

دوره 153 1  شماره 

صفحات  -

تاریخ انتشار 2015